RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity
R. Angioni, M. Bonfanti, N. Caporale, R. Sanchez-Rodriguez, F. Munari, A. Savino, D. Buratto, I. Pagani, N. Bertoldi, C. Zanon, P. Ferrari, E. Ricciardelli, C. Putaggio, S. Ghezzi, F. Elli, , G. Testa
The paper identifies RAGE as a novel receptor for SARS-CoV-2 that mediates monocyte infection and contributes to COVID-19 severity through single-cell analysis of immune responses.
bioRxiv · May 22, 2022Immunology