Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics
B. Budeus, A. Kibler, M. Brauser, E. Homp, K. Bronischewski, A. Ross, A. Goergens, M. A. Weniger, J. Dunst, T. Kreslavskiy, S. Vitoriano, F. Murke, C. C. Oakes, P. Rusch, D. Andrikos, , M. Seifert
This study shows that human cord blood B cells are mature and functional but have distinct transcriptional programs and rapid, transient response dynamics compared to adult B cells.
bioRxiv · Aug 11, 2020 · PreprintImmunology