Topoisomerase IIβ Kinase: A protein processed from HIV-1 envelope by cysteine proteases
Hema Verma, Satyajit Mukhopadhyay, Balakrishna S Lokeswara, Ritika Das, Abhash Kumar, Sangeetha Balasubramanian, Anand Kumar Kondapi
This study identifies TopoII{beta}K, a conserved HIV-1 envelope-derived polypeptide produced by cysteine proteases in endolysosomes during early infection.
bioRxiv · Oct 28, 2026 · PreprintMolecular Biology