Ongoing HIV replication in lymph node sanctuary sites in treated patients contributes to the total latent HIV at a very slow rate.
Sasan Paryad-Zanjani, Aditya Jagarapu, Michael J. Piovoso, Ryan Zurakowski
This study models HIV dynamics in lymph node sanctuary sites under antiretroviral therapy and finds that ongoing replication contributes very slowly to the total latent HIV pool.
bioRxiv · Feb 18, 2023 · PreprintSystems Biology