The effect of circulating neutralizing antibodies on the replication of SARS-CoV-2 variants following post-vaccination infections.
Miguel Garcia-Knight, John Daniel Kelly, Scott Lu, Michel Tassetto, Sarah A. Goldberg, Amethyst Zhang, Jesus Pineda-Ramirez, Khamal Anglin, Michelle C. Davidson, Jessica Y. Chen, Maya Fortes-Cobby, Sara Park, Ana Martinez, Matthew So, Aidan Donovan, , Raul Andino
This study examines how pre-existing neutralizing antibodies affect viral shedding in post-vaccination SARS-CoV-2 infections, finding that higher titers reduce viral load and duration but are less effective against Omicron variants.
JCI Insight · Mar 9, 2025Peer-reviewedImmunology