Author

Aiguo Xia

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Fan JiniD· 4 shared Lu PuiD· 3 shared Shuai YangiD· 3 shared Lei Ni· 2 shared Rongrong ZhangiD· 2 shared Shengwei FuiD· 2 shared Yajia HuangiD· 2 shared Bing LiiD· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersSynthetic Biology

Fan JinORCID

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Author profile →

4 papers

Recent·Most cited

High-throughput, microscopy-based screening, and quantification of genetic elements

Rongrong Zhang, Yajia Huang, Mei Li, Lei Wang, Bing Li, Aiguo Xia, Ye Li, Shuai Yang, Fan Jin

This paper introduces a high-throughput microscopy platform for screening genetic elements, identifying robust promoters and enabling single-cell phenotyping.

mLife · Dec 1, 2023Peer-reviewedMolecular Biology

Programming the lifestyles of engineered bacteria for cancer therapy

Shengwei Fu, Rongrong Zhang, Yanmei Gao, Jiarui Xiong, Ye Li, Lu Pu, Aiguo Xia, Fan Jin

This paper develops a genetic circuit to program bacterial lifestyles in cancer therapy using NIR light, improving therapeutic efficacy through precise control of bacterial behavior.

National Science Review · Feb 11, 2023Peer-reviewedSynthetic Biology

Engineering Gac/Rsm signaling cascade for optogenetic induction of pathogenicity switch in Pseudomonas aeruginosa

Xinyi Cheng, Lu Pu, Shengwei Fu, Aiguo Xia, Shuqiang Huang, Lei Ni, Xiaochen Xing, Shuai Yang, Fan Jin

This paper introduces an optogenetic system to control bacterial pathogenicity in specific host tissues by engineering the Gac/Rsm signaling cascade in Pseudomonas aeruginosa.

ACS Synthetic Biology · Jun 2, 2021Peer-reviewedSynthetic Biology

Optogenetics reprogramming of planktonic cells for biofilm formation

Aiguo Xia, Shuai Yang, Yajia Huang, Zhenyu Jin, Lei Ni, Lu Pu, Guang Yang, Fan Jin

This study develops ATI, a method to control biofilm formation in Pseudomonas aeruginosa by manipulating single-cell behaviors through optogenetics and tracking.

bioRxiv · Dec 4, 2017 · PreprintMicrobiology