Author

Akinchan Kumar

Luxembourg Institute of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bassam JanjiiD· 2 shared A. ConstantinescuiD· 1 shared Alaa BadreddineiD· 1 shared Andy ChevignéiD· 1 shared Axelle BerrouiD· 1 shared Bernard A. MalavaudiD· 1 shared Catherine Mazerolles· 1 shared Delphine Colignon· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Bassam JanjiORCID

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Author profile →

3 papers

Recent·Most cited

Targeting the Atypical Chemokine Receptor 2 (ACKR2) improves the benefit of anti-PD-1 immunotherapy in melanoma

Muhammad Zaeem Noman, Martyna Szpakowska, Malina Xiao, Ruize Gao, Kris Van Moer, Akinchan Kumar, Markus W. Ollert, Guy Berchem, Andy Chevigné, Bassam Janji

This study shows that targeting ACKR2 enhances anti-PD-1 immunotherapy efficacy in melanoma by improving the tumor microenvironment and immune cell infiltration.

OncoImmunology · Apr 18, 2025Peer-reviewedCancer Biology

ALDH1 subtype-specific inhibitor targets key cancerous epithelial cell populations in aggressive subtypes of breast cancer

Raquel Pequerul, A. Constantinescu, Bassam Janji, Akinchan Kumar, Xavier Parés, Òscar Palacios, Delphine Colignon, Axelle Berrou, Guy Fournet, Paul BERCHARD, Guillaume Martin, Ismail Ceylan, Rocio Rebollido-Ríos, Jaume Farrés, Mileidys Perez-Alea

This study identifies ALDH1A3 as a therapeutic target in aggressive breast cancers and develops ABD0171, a selective inhibitor showing antitumor and antimetastatic effects.

bioRxiv · Oct 18, 2024 · PreprintCancer Biology

Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention

Akinchan Kumar, Alaa Badreddine, Karim Azzag, Yasenya Kasikçi, Marie Laure Quintyn Ranty, Falek Zaidi, Nathalie Serret, Catherine Mazerolles, Bernard A. Malavaud, Marco Antonio Mendoza-Parra, Laurence Vandel, Hinrich Gronemeyer

The paper identifies patient-specific deregulated regulatory networks in prostate cancer to inform personalized therapeutic strategies.

bioRxiv · Jul 11, 2019 · PreprintGenomics