Author

Alesja Dernst

University of Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas Jaensch· 1 shared Antonia Wagener· 1 shared Bianca Martin· 1 shared Christina F. BuddeniD· 1 shared Eicke LatziD· 1 shared Felix MeissneriD· 1 shared Fraser Duthie· 1 shared Harald Andreas Färber· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Andreas Jaensch

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Butyrate and propionate are microbial danger signals that activate the NLRP3-inflammasome in human macrophages in the presence of TLR stimulation

Wei Wang, Alesja Dernst, Bianca Martin, Lucía Lorenzi, Maria Cadefau-Fabregat, Kshiti Meera Phulphagar, Antonia Wagener, Christina F. Budden, Neil Stair, Theresa Maria Wagner, Harald Andreas Färber, Andreas Jaensch, Rainer Stahl, Fraser Duthie, Susanne V. Schmidt, , M. S. J. Mangan

The paper shows that butyrate and propionate activate the NLRP3 inflammasome in human macrophages when combined with TLR agonists, through HDAC inhibition and epigenetic changes.

Cell Reports · Sep 1, 2024Peer-reviewedImmunology