Canonical AREs are tumor suppressive regulatory elements in the prostate
Xuanrong Chen, Michael A. Augello, Deli Liu, Kevin Lin, Alex Hakansson, Martin Sjöström, Francesca Khani, Lesa Dayal Deonarine, Yang Liu, Jaida Travascio-Green, Jiansheng Wu, Un In Chan, Jude N. Owiredu, Massimo F. Loda, Felix Yi-Chung Feng, , Christopher E. Barbieri
This study identifies canonical AREs as tumor suppressive regulatory elements in prostate cancer, showing their reactivation can induce death in AR+ cancer cells and is linked to better prognosis.
Nature Communications · Dec 13, 2024Peer-reviewedCancer Biology