Whole Blood Deep Immunophenotyping and Platelet-Leukocyte Aggregate Quantification by Spectral Flow Cytometry
Haiyuan Ding, Krista R. Gerbino, Katy Gilham, Yawei Tong, Alex Hu, Elaine L. Huang, Ella Zabriskie, Tahsin Ozpolat, Li Guo, Scott C. Brakenridge
The paper develops a 27-color spectral flow cytometry protocol to quantify platelet-leukocyte aggregates across multiple leukocyte subsets in human whole blood, revealing their distribution and behavior in health and disease.
bioRxiv · Oct 7, 2026 · PreprintImmunology