NK Cells Engineered with a Chimeric Antigen Receptor Delay HIV Rebound and Reshape HIV Reservoir Composition
Yuan Shi, Izra Abbaali, William Harvey, Matthew Kostelny, Hongying Chen, Alexander Gonzalez, Melanie Dimapasoc, Suwen Li, Amélie Montel‐Hagen, Christopher S. Seet, Catherine A. Blish, Jerome A. Zack, Jocelyn T. Kim
This study shows that engineered NK cells with a CD4-based CAR delay HIV rebound and alter the reservoir's composition in humanized mice.
Nature Communications · Oct 27, 2026Peer-reviewedImmunology