Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander Plotnikov, Haim Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth, Efrat Shema
This study investigates dual targeting of HDACs and MYC in H3-K27M pediatric gliomas, showing synergistic effects in reducing cell viability and tumor growth.
bioRxiv · Feb 5, 2024Cancer Biology