Single-cell dissection of cell hierarchies in urine-derived stem cells - application to chondrogenesis and general scalability
Alexander Schulz, Emily M Brockmann, Miriam Zentgraf, Andreas S. Baur, Steffen Uebe, Arif Bülent Ekici, Mark Dedden, Sebastian Zundler, Christian Thomas Thiel
The paper establishes urine-derived stem cells (USCs) as a non-invasive source for chondrogenesis, revealing cell hierarchy and differentiation trajectories through single-cell RNA sequencing.
bioRxiv · Sep 26, 2025 · PreprintGenetics