Longitudinal TCR repertoires in ulcerative colitis patients show features distinguishing disease states
Sabahat Rahman, Beiya Xu, Matthew Farah, Amanda Kwok, Jacob Varghese, Amir Hossein Daraie, Joseph L. Greenstein, Casey Overby Taylor, Nidhi Soley, April Yan, Ishan Vatsaraj, Carl Harris, Joanna Melia, Kristi Briggs
This study analyzes TCR repertoires from ulcerative colitis patients over time, identifying Vβ gene usage and K-mer enrichment differences between flare and remission states.
Inflammatory Bowel Diseases · Mar 13, 2026Peer-reviewedImmunology