Cancer stem cell transcriptomic signatures reveal patient-to-patient heterogeneity emphasizing the need for patient-specific ovarian cancer targets
Matthew S. Jung, Lindsey J. Davis, Audrey A. Birdwell, Jisun Kang, Colleen Feng, Amelia Pi, Sue Chin LEE, Sandra Davern, Rachel Patton McCord, Junming Yue, Wenjing Zhang, Won-Young Choi, Rachel S. Perkins
The paper identifies patient-specific transcriptomic signatures of ovarian cancer stem cells (CSCs) using RNA-seq, revealing isoform-level heterogeneity that drives stemness and drug resistance.
bioRxiv · Oct 2, 2026 · PreprintCancer Biology