Author

Amelie Menge

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Lewis ElsoniD· 2 shared Martin P. SchwalmiD· 2 shared Stefan KnappiD· 2 shared Susanne MülleriD· 2 shared Ana CorrioneroiD· 1 shared Andreas KrämeriD· 1 shared Benedict‐Tilman BergeriD· 1 shared Daniela S. KrauseiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Lewis ElsonORCID

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Author profile →

2 papers

Recent·Most cited

Repurposing of the RIPK1 selective benzooxazepin-4-one scaffold for the development of a type-III LIMK1/2 inhibitor

Sebastian Mandel, Thomas Hanke, Sebastian Mathea, Deep Chatterjee, Hayuningbudi Saraswati, Benedict‐Tilman Berger, Martin P. Schwalm, Satoshi Yamamoto, Michiko Tawada, Terufumi Takagi, Mahmood Ahmed, Sandra Röhm, Ana Corrionero, Patricia Alfonso, Maria Baena, , Stefan Knapp

The paper repurposes a benzoxazepinone scaffold originally designed for RIPK1 inhibition to develop a novel type-III LIMK1/2 inhibitor with high selectivity.

ACS Chemical Biology · Apr 14, 2025Peer-reviewedBiochemistry

Functional characterization of pathway inhibitors for the ubiquitin-proteasome system (UPS) as tool compounds for CRBN and VHL-mediated targeted protein degradation

Martin P. Schwalm, Amelie Menge, Lewis Elson, Francesco Greco, Matthew B. Robers, Susanne Müller, Stefan Knapp

The paper evaluates diverse ubiquitin pathway inhibitors as controls for CRBN and VHL-mediated protein degradation, assessing their potency and toxicity using the HiBiT system and high content assays.

ACS Chemical Biology · Jan 3, 2025Peer-reviewedBiochemistry