Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification
Clark L. Hendrickson, Ira L. Blitz, Amina Hussein, Kitt D. Paraiso, Jin Cho, Michael W. Klymkowsky, Matthew J. Kofron, Ken W.Y. Cho
This study identifies Foxi2 and Sox3 as master regulators of ectoderm specification in Xenopus, showing they control gene expression and epigenetic landscape through super-enhancers.
bioRxiv · Jan 9, 2025 · PreprintDevelopmental Biology