Author

Amit Kugler

Uppsala University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioengineering· 1

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Karin StensjöiD· 3 shared Bhavik Shah· 1 shared Cecilia BlikstadiD· 1 shared Conrad SchumanniD· 1 shared Gustav BerggreniD· 1 shared Henrik LandiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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3 shared papersSystems Biology

Karin StensjöORCID

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3 papers

Recent·Most cited

Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Conrad Schumann, Amit Kugler, Bhavik Shah, Gustav Berggren, Henrik Land, Cecilia Blikstad, Karin Stensjö

This paper improves isobutene production in Synechocystis sp. PCC 6803 by engineering the promiscuous RnKICD enzyme to enhance its selectivity for KIC over HPP, resulting in a 4-fold increase in isobutene yield.

Microbial Cell Factories · Apr 23, 2025Peer-reviewedBioengineering

Machine learning predicts system-wide metabolic flux control in cyanobacteria

Amit Kugler, Karin Stensjö

This paper introduces ARCTICA, a framework combining constraint-based modeling and machine learning to predict metabolic flux control in cyanobacteria, identifying key enzymes and reactions that limit photosynthetic activity.

Metabolic Engineering · Feb 21, 2024Peer-reviewedSystems Biology

Optimal energy and redox metabolism in the cyanobacterium Synechocystis sp. PCC 6803

Amit Kugler, Karin Stensjö

The paper uses metabolic modeling to analyze energy and redox balance in Synechocystis sp. PCC 6803 for optimizing bio-alkene production.

npj Systems Biology and Applications · Sep 22, 2023Peer-reviewedSystems Biology