Author

Amy Fernandez

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Benjamin Galeota-SprungiD· 3 shared P. D. SniegowskiiD· 3 shared Cecilia Wright· 1 shared Crystal Huang· 1 shared Erik Pritchard· 1 shared Ronan Soto Tejada· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersEvolutionary Biology

Benjamin Galeota-SprungORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Diploidy alters the path of fluconazole adaptation in Candida glabrata

Benjamin Galeota-Sprung, Amy Fernandez, Cecilia Wright, Ronan Soto Tejada, Paul Sniegowski

This study shows diploids have an evolvability advantage over haploids in adapting to fluconazole in Candida glabrata, with distinct mutation patterns under different drug concentrations.

bioRxiv · Oct 6, 2026 · PreprintEvolutionary Biology

Directed evolution for cell separation in natural isolates of budding yeast reveals selection to deactivate AMN1 and the Rim101 pathway in haploids and selection in favor of Hawthorne's deletion in diploids

Benjamin Galeota-Sprung, Erik Pritchard, Crystal Huang, Amy Fernandez, P. D. Sniegowski

The paper evolves natural yeast isolates to select for cell separation, identifying AMN1 deactivation and Rim101 pathway mutations in haploids, and Hawthorne's deletion in diploids as key adaptations.

G3 Genes Genomes Genetics · Jan 23, 2026Peer-reviewedEvolutionary Biology

Changes to the mtDNA copy number during yeast culture growth

Benjamin Galeota-Sprung, Amy Fernandez, Paul Sniegowski

This study shows that mtDNA copy number in yeast cultures increases up to fourfold during growth, with variations depending on metabolic state and strain.

Royal Society Open Science · Jul 1, 2022Peer-reviewedGenetics