Cancer BiologybioRxivPreprint
Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
Jonathan M Harnoss, Adrien Le Thomas, Scot A Marsters…·Avi Ashkenazi
This study shows that disrupting IRE1α's kinase domain reduces multiple myeloma tumor growth and enhances treatment efficacy, suggesting it as a therapeutic target.
DOI 10.1101/495242