Author

Ananth Grama

Purdue University;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Shahin Mohammadi· 4 shared Baharak Saberidokht· 1 shared Mengbo WangiD· 1 shared Nadia Atallah Lanman· 1 shared Shankar Subramaniam· 1 shared Shourya VermaiD· 1 shared Simran D Kadadi· 1 shared

Activity by Year

2014-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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4 shared papersSystems Biology

Shahin Mohammadi

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Author profile →

4 papers

Recent·Most cited

Spectral Adaptive Repositioning for Flow-Based Single-Cell Perturbation Modeling

Shourya Verma, Mengbo Wang, Simran D Kadadi, Nadia Atallah Lanman, Shahin Mohammadi, Ananth Grama

SPEAR predicts cellular responses to perturbations by adaptively repositioning genes in a co-expression network using spectral encoding and generative modeling.

bioRxiv · Nov 4, 2026 · PreprintBioinformatics

A convex optimization approach for identification of human tissue-specific interactomes

Shahin Mohammadi, Ananth Grama

This paper introduces a convex optimization method to construct human tissue-specific interactomes, showing improved performance over existing methods and demonstrating applications in disease pathway analysis.

bioRxiv · May 5, 2016Systems Biology

A novel method to enhance the sensitivity of marker detection using a refined hierarchical prior of tissue similarities

Shahin Mohammadi, Ananth Grama

This paper introduces a statistical method to improve marker detection by refining tissue similarity priors, showing better performance in identifying tissue-selective genes in immune and brain tissues.

bioRxiv · Jun 11, 2015 · PreprintSystems Biology

On the scope and limitations of baker’s yeast as a model organism for studying human tissue-specific pathways

Shahin Mohammadi, Baharak Saberidokht, Shankar Subramaniam, Ananth Grama

The paper assesses yeast's suitability as a model for human tissue-specific pathways and identifies gene subsets linked to diseases.

bioRxiv · Nov 26, 2014Systems Biology