A clinically annotated proteomic and histological resource of 1,000 colorectal cancers
Arber Qoku, Niklas Ullrich, Felipe Miranda, Tessa Rosenthal, Andreas Keil, Jakob Vowinckel, Mario Salomon Dueker, Sandra Ruengeling, Linde-Allegra Rosen, Fabio Bennet Gaetje, Martin Zielke, Tim Tucholski, Franz F. Dressler, Stefan Kueffer, Alexander Otto Koenig, , Hanibal Bohnenberger
Deep proteomics of 997 treatment-naïve colorectal cancers defines six subgroups, splitting chromosomally unstable tumors into three and revealing a rare adverse subgroup, with H&E slide benchmarks.
bioRxiv · Oct 24, 2026 · PreprintCancer Biology✦ In-depth digest