Cis- and trans-eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia
S. Taylor Head, Felipe Segato Dezem, Andrei Todor, Jingjing Yang, Jasmine Plummer, Simon A. Gayther, Siddhartha Kar, Joellen M. Schildkraut, Michael P. Epstein
This study performs cis- and trans-eQTL TWAS on breast and ovarian cancer data to identify 101 and 8 risk-associated genes, respectively, with several driven by trans-eQTLs.
bioRxiv · Nov 9, 2023 · PreprintGenetics