Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE
Sam Crowl, Maeve Bella Coleman, Andrew Chaphiv, Ben T. Jordan, Kristen M. Naegle
This paper introduces PTM-POSE, a computational pipeline to analyze how alternative splicing affects post-translational modifications, and finds that 32% of PTMs are excluded from at least one Ensembl isoform.
Cell Systems · Jul 1, 2025Peer-reviewedSystems Biology