Author

Angus G Cunningham

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:software / tool· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Chris P. BarnesiD· 2 shared Anastasiia Shcherbakova· 1 shared Linda DekkeriD· 1 shared McClain ThieliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersBioinformatics

Chris P. BarnesORCID

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2 papers

Recent·Most cited

Effects of Structural Reward Shaping on Biophysical Properties in RL-Trained Plasmid Generators

McClain Thiel, Angus G Cunningham, Chris P. Barnes

This paper evaluates RL and SFT for plasmid generation, finding RL achieves higher quality-control pass rates and converges to real plasmid distributions in 3-mer composition and minimum free energy density.

bioRxiv · May 29, 2026 · PreprintBioinformatics

Generative design and construction of functional plasmids with a DNA language model

Angus G Cunningham, Linda Dekker, Anastasiia Shcherbakova, Chris P. Barnes

This paper develops a pipeline to generate functional E. coli plasmids using a DNA language model, resulting in three validated synthetic plasmids.

bioRxiv · Dec 7, 2025 · PreprintSynthetic Biology