Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune response
Inci Ramírez-Bello, Tomás López, Rafaela Espinosa, Anisa Ghosh, Kassidy Green, Lidia Riaño‐Umbarila, Carlos Gaspar-Castillo, Catalina Aguilera-Flores, Celia Mercedes Alpuche-Aranda, Susana López, Rebecca M. DuBois, Carlos Federico Arias
This paper identifies three neutralizing monoclonal antibodies against HAstV-VA1 and maps their epitopes, revealing four antigenic sites and immune pressure-driven mutations in a patient with encephalitis.
Journal of Virology · Jun 25, 2024Peer-reviewedMicrobiology