Hi-C detects genomic structural variants in peripheral blood of pediatric leukemia patients
Claire Mallard, Michael J.G. Johnston, Anna Bobyn, Ana Nikolić, Bob Argiropoulos, Jennifer Ai-wen Chan, Gregory M.T. Guilcher, Marco Gallo
The paper demonstrates that Hi-C can detect structural variants, including translocations, in peripheral blood samples of pediatric B-ALL patients, offering a non-invasive alternative to bone marrow biopsies.
Molecular Case Studies · Jan 1, 2022Peer-reviewedGenetic & Genomic Medicine