A spectrum of clinically-identified cysteine mutations in fibulin-3 (EFEMP1) highlight its disulfide bonding complexity and potential to induce stress response activation
Gracen E. Collier, Anna L Roovers, John D. Hulleman
The paper examines how cysteine mutations in FBLN3 affect its structure, secretion, and stress response, revealing varied biochemical outcomes and potential disease implications.
Scientific Reports · Aug 16, 2025Peer-reviewedBiochemistry