Longitudinal cell-free DNA methylome and fragmentome profiles in health uncover signatures of cell type and demographic origin
Mio Aerden, Tatjana Jatsenko, Kaat Leroy, Kobe De Ridder, Anna Nootens, Valentina Piatti, Koenraad Devriendt, Joris Robert Vermeesch, Huiwen Che, Bernard Thienpont
The paper analyzes cfDNA methylome and fragmentome profiles from healthy individuals to identify cell-type and demographic signatures influencing cfDNA characteristics.
Genome Medicine · Apr 9, 2026Peer-reviewedGenomics