Polyphosphate metabolism genes are associated with hydroxyapatite biomineralization capacity in a novel hydrogenotrophic methanogen Methanobacterium AMB_03
Faez Alexandre Robin-Champgneul, Abhijeet Singh, Siddhant Sharma, Oleg Tkachenko, Jakob Thyr, Sotiris Sidiropoulos, Anna Schnurer, Tomasz Zajkowski, Tetyana Budnyak, Anna Neubeck
This study links polyphosphate metabolism genes to hydroxyapatite biomineralization in Methanobacterium AMB_03, showing that polyphosphate synthesis enables carbonate-substituted hydroxyapatite precipitation under phosphate-enriched conditions.
bioRxiv · Nov 9, 2026 · PreprintMicrobiology