Author

Anna Singer

Benson Hill Biosystems (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 3 Approach:experimental assay· 3 Research Focus:benchmarking· 2 Organism:E. coli· 2 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Organism:plant (other)· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Emma January· 3 shared Matthew B. BegemanniD· 3 shared Benjamin N. Gray· 2 shared Yonghua He· 2 shared Alex Jordan· 1 shared Allison J.N. Antonakos· 1 shared Chase L. BeiseliD· 1 shared Colin S. MaxwelliD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Emma January

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Comparative characterization of Cas12a2 orthologs identifies high-activity nucleases for programmable cell elimination

Anna Singer, Emma January, Erin K. Zess, Allison J.N. Antonakos, Matthew B. Begemann

The paper characterizes nine Cas12a2 orthologs, identifies three with high DNA collateral activity, and defines their PFS preferences and mismatch tolerance.

bioRxiv · Jul 7, 2026 · PreprintMolecular Biology

Rapid and scalable characterization of CRISPR technologies using an E. coli cell-free transcription-translation system

Ryan Marshall, Colin S. Maxwell, Scott P. Collins, Thomas Jacobsen, Michelle L. Luo, Matthew B. Begemann, Benjamin N. Gray, Emma January, Anna Singer, Yonghua He, Chase L. Beisel, Vincent Noireaux

This paper introduces an E. coli cell-free system to rapidly and scalably characterize CRISPR technologies, including DNA cleavage, gene repression, and anti-CRISPR activity.

Molecular Cell · Jan 1, 2018Peer-reviewedSynthetic Biology

Characterization and Validation of a Novel Group of Type V, Class 2 Nucleases for in vivo Genome Editing

Matthew B. Begemann, Benjamin N. Gray, Emma January, Anna Singer, Dylan C. Kesler, Yonghua He, Haijun Liu, Hongjie Guo, Alex Jordan, Thomas P. Brutnell, Todd C. Mockler, Mohammed Oufattole

The paper identifies and validates a novel Type V, Class 2 CRISPR nuclease system (Cms1) from bacterial species that can efficiently generate indel mutations in rice.

bioRxiv · Sep 27, 2017 · PreprintMolecular Biology