TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis
Zlata Gvozdenov, Anusmita Biswas, Audrey Yi Tyan Peng, Zeno Barcutean, Daniel R. Gestaut, Judith Frydman, Kevin Struhl, Brian Freeman
This study shows TRiC/CCT regulates RNA polymerase II activity in the nucleus, affecting RNA homeostasis by modulating nascent RNA production.
Molecular Cell · Sep 1, 2026Peer-reviewedMolecular Biology