The SLC15A4-LAMTOR1 interaction licenses endolysosomal TLR-mediated mTOR signaling and inflammatory cytokine production
Tzu-Yuan Chiu, Peter-Rory Hall, Daniel C. Lazar, Arthur Kim, Stefano Forli, Andrew B. Ward, John Ross Teijaro, Christopher G. Parker
This paper identifies a direct interaction between SLC15A4 and LAMTOR1 that is required for endolysosomal TLR-mediated mTOR signaling and inflammatory cytokine production.
bioRxiv · Jun 9, 2026 · PreprintImmunology