Cross-omic dissection reveals locus-specific heterogeneity and antagonistic pleiotropy between Alzheimer's disease and type 2 diabetes
Emmanuel Olorunleke Adewuyi, Asa Auta, Olayinka Sunday Okoh, Kaja Kristine Selmer, Kristina Gervin, Dale R. Nyholt, Gavin F Pereira
This paper uses cross-omic analyses to show that Alzheimer's disease and type 2 diabetes share some genetic links but also exhibit locus-specific heterogeneity and antagonistic pleiotropy.
medRxiv · Mar 25, 2026 · PreprintGenetic & Genomic Medicine