Rapid nuclear exclusion of Hcm1 in aging Saccharomyces cerevisiae leads to vacuolar alkalization and replicative senescence
Ata Ghavidel, Kunal Baxi, Martin A. Prusinkiewicz, Cynthia L. Swan, Zach R. Belak, Christopher H. Eskiw, Carlos Egydio de Carvalho, Troy A. A. Harkness
The paper shows that Hcm1 nuclear exclusion in aging yeast leads to vacuolar alkalization and reduced replicative lifespan.
G3 Genes Genomes Genetics · Mar 8, 2018Peer-reviewedGenetics