Author

Aydan Askarova

UK Dementia Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alexi NottiD· 3 shared Sarah J. MarziiD· 3 shared Reuben M YaaiD· 2 shared Ahmad-Reza EhyaeiiD· 1 shared Alan E MurphyiD· 1 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Australian Imaging Biomarkers and Lifestyle Study· 1 shared Boris LenhardiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Alexi NottORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell type-specific histone acetylation landscape in Alzheimer's disease reveals a putative role of MITF in microglia

Charbel Gergian, Paulina Urbanaviciute, Philippa M. Wells, Janis Lisa Transfeld, Aydan Askarova, Reuben M Yaa, Yukyee Wu, Kevin Chris Ziegler, Christian K. Nickl, Martina P. Pasillas, Johannes C. M. Schlachetzki, Inge R. Holtman, Peter T. Nelson, Robert A. Rissman, James B. Brewer, , Alexi Nott

This study identifies cell-type-specific histone acetylation changes in Alzheimer's disease, highlighting MITF's potential role in microglial dysfunction.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience

Genetic drivers of progression in Alzheimers disease are distinct from disease risk

Celeste E. Cohen, Shane Fernandez, Ümran Yaman, Ahmad-Reza Ehyaei, Eleftheria Kodosaki, Aydan Askarova, Tenielle Porter, Eleanor O’Brien, Australian Imaging Biomarkers and Lifestyle Study, Alzheimer’s Disease Neuroimaging Initiative, Paul T. Maruff, Alexi Nott, John Hardy, Simon Matthew Laws, Dervis A. M. Salih, Maryam Shoai

The paper identifies genetic factors associated with Alzheimer's disease progression using GWAS and longitudinal data, finding distinct genetic drivers from disease risk.

Alzheimer s Research & Therapy · Apr 25, 2026Peer-reviewedGenetic & Genomic Medicine

Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways

Aydan Askarova, Reuben M Yaa, Sarah J. Marzi, Alexi Nott

The paper links genetic risk for neurodegenerative diseases to microglial pathways using genomic and computational methods.

PLoS Genetics · Apr 9, 2025Peer-reviewedGenomics

Predicting gene expression from histone marks using chromatin deep learning models depends on histone mark function, regulatory distance and cellular states

Alan E Murphy, Aydan Askarova, Boris Lenhard, Nathan Skene, Sarah J. Marzi

This study shows that histone mark function, genomic distance, and cellular states collectively influence gene expression predictions using deep learning models, with no single mark consistently predicting expression across contexts.

Nucleic Acids Research · Dec 9, 2024Peer-reviewedGenomics