Author

Azadeh Jadali

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Kelvin Y. KwaniD· 5 shared Ronald P. HartiD· 3 shared Zhiping P. PangiD· 3 shared Edward A. Martinez· 2 shared Jingyun QiuiD· 2 shared Julie Zhouli NiiD· 2 shared Le WangiD· 2 shared Matteo BernabucciiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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5 shared papersNeuroscience

Kelvin Y. KwanORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CHD7 binds distinct regions in the Sox11 locus to regulate neuronal differentiation

Edward A. Martinez, Azadeh Jadali, Jingyun Qiu, Anna Maria Hinman, Julie Zhouli Ni, Jihyun Kim, Kelvin Y. Kwan

This study identifies CHD7 binding sites in the Sox11 locus and shows how CHD7 regulates neuronal differentiation through chromatin remodeling and CTCF-marked insulators.

bioRxiv · Apr 2, 2025 · PreprintMolecular Biology

CHD7 binds to insulators during neuronal differentiation

Jingyun Qiu, Azadeh Jadali, Edward A. Martinez, Zhichao Song, Julie Zhouli Ni, Kelvin Y. Kwan

The paper shows CHD7 binds to insulator regions during neuronal differentiation, regulating gene expression through interactions with CTCF.

bioRxiv · Mar 28, 2025 · PreprintMolecular Biology

Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic Mechanism

Le Wang, Vincent R. Mirabella, Rujia Dai, Xiao Yi Su, Ranjie Xu, Azadeh Jadali, Matteo Bernabucci, Ishnoor Singh, Yu Chen, Jianghua Tian, Peng Jiang, Kelvin Y. Kwan, ChangHui Pak, Chunyu Liu, Davide Comoletti, , Zhiping P. Pang

The paper investigates the impact of the NLGN3 R451C mutation on human neurons, finding it reduces protein levels but enhances excitatory synapses, potentially contributing to ASD pathogenesis.

Molecular Psychiatry · Oct 24, 2022Peer-reviewedNeuroscience

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

Dina Popova, Isabel Gameiro‐Ros, Mark M. Youssef, Petronio D. Zalamea, Ayeshia Morris, Iya Prytkova, Azadeh Jadali, Kelvin Y. Kwan, Chella Kamarajan, Jessica E. Salvatore, Xiaoling Xuei, David Balin Chorlian, Bernice Porjesz A, Samuel Kuperman C, Danielle M. Dick, , Ronald P. Hart

This study shows that KCNJ6 noncoding variants increase excitability in human glutamatergic neurons, an effect reversed by ethanol exposure.

Molecular Psychiatry · Oct 7, 2022Peer-reviewedNeuroscience

Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimers Disease

Mengmeng Jin, Ranjie Xu, Le Wang, Mahabub Maraj Alam, Ziyuan Ma, Sining Zhu, Alessandra Cadete Martini, Azadeh Jadali, Matteo Bernabucci, Ping Xie, Kelvin Y. Kwan, Zhiping P. Pang, Elizabeth Head, Ying Liu, Ronald P. Hart, Peng Jiang

bioRxiv · Dec 22, 2021 · PreprintNeuroscience