A Structural Signature Motif Enlightens the Origin and Diversification of Nuclear Receptors
B. Beinsteiner, G. V. Markov, S. Erb, Y. Chebaro, A. G. McEwen, S. Sanglier Cianferani, V. Laudet, D. Moras, I. Billas
This study identifies a structural motif, the {pi}-turn, as critical for nuclear receptor dimerization and functional diversification across evolution.
bioRxiv · Nov 18, 2020Evolutionary Biology