Author

B. Binukumar

National Institute of Mental Health and Neurosciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:whole-exome sequencing· 3 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Shyamsundar· 5 shared Bangalore N. GangadhariD· 5 shared Bhupesh MehtaiD· 5 shared Biju ViswanathiD· 5 shared Deepak JayarajaniD· 5 shared Janardhan Y. C. ReddyiD· 5 shared Janardhanan C. NarayanaswamyiD· 5 shared John P. JohniD· 5 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenetic & Genomic Medicine

A. Shyamsundar

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Author profile →

5 papers

Recent·Most cited

Whole Exome Sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes

Suhas Ganesh, Alekhya Vemula, Samsiddhi Bhattacharjee, Kezia Mathew, Dhruva Ithal, Karthick Navin, Ravi Kumar Nadella, Biju Viswanath, Patrick F. Sullivan, Naren Prahalada Rao, Janardhanan C. Narayanaswamy, Palanimuthu Thangaraju Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, , Meera Purushottam

This study uses whole exome sequencing in families with multiple affected individuals to identify rare variants in genes associated with both Mendelian and complex neuropsychiatric syndromes.

Scientific Reports · Dec 7, 2022Peer-reviewedGenetic & Genomic Medicine

Sample size requirement for achieving multisite harmonization using structural brain MRI features

Pravesh Parekh, Gaurav Vivek Bhalerao, Biju Viswanath, Naren Prahalada Rao, Janardhanan C. Narayanaswamy, Palanimuthu Thangaraju Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Odity Mukherjee, Meera Purushottam, Bhupesh Mehta, Kandavel Thennarasu, B. Binukumar, Jitender S. Saini, , Ganesan Venkatasubramanian

This study determines the minimum sample size needed for multisite harmonization using structural brain MRI features and shows how sample size requirements increase with site variability.

NeuroImage · Nov 24, 2022Peer-reviewedNeuroscience

Analysis of whole exome sequencing in severe mental illness hints at selection of brain development and immune related genes

Jayant Mahadevan, Ajai Kumar Pathak, Alekhya Vemula, Ravi Kumar Nadella, Biju Viswanath, Sanjeev Jain, Naren Prahalada Rao, Janardhanan C. Narayanaswamy, Palanimuthu Thangaraju Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Ganesan Venkatasubramanian, John P. John, Meera Purushottam, , Mayukh Mondal

The paper analyzes whole exome sequencing data from individuals with severe mental illness to identify genes under positive selection and their biological functions.

Scientific Reports · Oct 26, 2021Peer-reviewedGenetic & Genomic Medicine

Adverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses

Amala Someshwar, Bharath Holla, Preeti Pansari Agarwal, Anza Thomas, Anand Jose, Boban Joseph, Birudu Raju, Hariprasad Karle, Moorthy Muthukumaran, Prabhath Gujjadi Kodancha, Pramod Kumar, Preethi Veerappa Reddy, Ravi Kumar Nadella, Sanjay T Naik, Sayantanava Mitra, , Mahendra S. Rao

The paper examines the relationship between adverse childhood experiences (ACEs) and the age of onset of psychiatric diagnoses in individuals from families with multiple affected members.

Australian & New Zealand Journal of Psychiatry · Jun 15, 2020Peer-reviewedNeuroscience

INDEX-db: The Indian Exome Reference database (Phase-I)

Husayn Ahmed Pallikonda, V. Vidhya, Ravi Prabhakar More, Biju Viswanath, Sanjeev Jain, Mahendra S. Rao, Odity Mukherjee, Naren Prahalada Rao, Janardhanan C. Narayanaswamy, Palanimuthu Thangaraju Sivakumar, ArunKandaswamy, MuralidharanKesavan, Urvakhsh-Meherwan Mehta, GanesanVenkatasubramanian, John P. John, , MahendraRao

The paper develops a database of coding variations from the Indian population to aid in understanding genotype-phenotype correlations and disease mechanisms.

Journal of Computational Biology · Jan 7, 2019Peer-reviewedGenomics