The basal level of gene expression associated with chromatin loosening shapes Waddington landscapes and controls cell differentiation
G. Flouriot, C. Jehanno, Y. le Page, P. le Goff, B. Boutin, D. Michel
This study shows that basal gene expression levels, linked to chromatin loosening, shape Waddington landscapes and control cell differentiation by influencing cellular dedifferentiation and epigenetic stability.
bioRxiv · Aug 16, 2019Cell Biology