Synthetic HNK-1 containing glycans provide insight into binding properties of serum antibodies from MAG-neuropathy patients
M. Bunyatov, M. A. Wolfert, R. Huizinga, M. W. Schreurs, B. C. Jacobs, G.-J. Boons
The paper develops a chemoenzymatic method to synthesize HNK-1 containing oligosaccharides and uses them to identify distinct binding preferences of serum antibodies from anti-MAG neuropathy patients.
bioRxiv · Jul 25, 2022Biochemistry