TLR5 signalling activates the alternative NF-κB signalling pathway in Cystic Fibrosis bronchial epithelial cells in response to infection with Prevotella histicola.
B. C. Schock, A. Bertelsen, S. J. Elborn
This study shows that P.histicola activates the alternative NF-κB pathway in CF bronchial epithelial cells via TLR5, while suppressing canonical NF-κB activation.
bioRxiv · Jun 24, 2020Cell Biology