Intracellular pH differentially regulates transcription of metabolic and signaling pathways in normal epithelial cells
R. R. Moreno, B. Czowski, L. Harris, J. F. Kuehn, K. A. White
The paper shows that intracellular pH changes regulate transcription of signaling and metabolic pathways in normal epithelial cells, with high pH increasing Notch1 and glycolytic gene expression.
bioRxiv · Jul 12, 2022Biochemistry