Balanced polymorphism at the Pgm-1 locus of the Pompeii worm Alvinella pompejana and its variant adaptability is only governed by two QE mutations at linked sites
A. Bioy, A.-S. Le Port, E. Sabourin, M. Verheye, P. Piccino, B. Faure, S. Hourdez, J. Mary, D. Jollivet
The paper identifies two amino-acid mutations in the Pgm-1 gene of Alvinella pompejana that govern thermal adaptation through a thermodynamic trade-off between thermostability and catalysis.
bioRxiv · Nov 22, 2021 · PreprintEvolutionary Biology