Pneumococcal genetic variability influences age-dependent bacterial carriage
P. H. C. Kremer, B. Ferwerda, H. J. Bootsma, N. Y. Rots, A. J. Wijmega-Monsuur, L. A. M. Sanders, K. Trzcinski, A. L. Wyllie, P. Turner, A. van der Ende, M. C. Brouwer, S. D. Bentley, D. van de Beek, J. A. Lees
This study identifies pneumococcal genetic factors associated with age-dependent carriage, suggesting vaccine formulations should target serotypes rather than proteins.
bioRxiv · Mar 3, 2021 · PreprintMicrobiology