Impact of Cancer-Associated Mutations in Hsh155/SF3b1 HEAT Repeats 9-12 on pre-mRNA Splicing in Saccharomyces cerevisiae
H. Kaur, B. Groubert, J. Paulson, S. McMillan, a. hoskins
This study tests the impact of SF3b1 mutations in HR9-12 on splicing in yeast, finding they support splicing and alter interactions with splicing factors.
bioRxiv · Feb 5, 2020Biochemistry