Computational modeling of methylation impact of AML drivers reveals new pathways and refines AML risk-stratification
B. Gurun, J. W. Tyner, E. Demir, B. J. Druker, P. T. Spellman
This paper uses supervised and unsupervised models to identify new methylation pathways and improve AML risk-stratification by analyzing epigenetic changes in progenitor cells.
bioRxiv · May 17, 2023 · PreprintCancer Biology