Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA
G. Finocchio, B. Koopal, A. Potocnik, C. Heijstek, M. Jinek, D. C. Swarts
This study reveals how SPARTA, a prokaryotic immune system, is activated by target DNA through structural changes that enable oligomerization and catalytic activity.
bioRxiv · Sep 23, 2023Biochemistry