B. Philipp

A patchwork pathway of apparently recent origin enables degradation of the synthetic buffer compound TRIS in bacteria

The paper discovers a recently evolved bacterial pathway for degrading TRIS, a synthetic buffer, through horizontal gene transfer and shows its global distribution.

Comparative analysis of bile-salt degradation in Sphingobium sp. strain Chol11 and P. stutzeri Chol1 reveals functional diversity of β-proteobacterial steroid degradation enzymes and suggests a novel reaction sequence for side-chain degradation involving a hydroxylation step

Proteome, bioinformatic and functional analyses reveal a distinct and conserved metabolic pathway for bile salt degradation in the Sphingomonadaceae