Antiviral effect of thiazolides relies on mitochondrial mild uncoupling
N. Hammad, C. Ransy, B. Pinson, J. Talmasson, C. Brechot, F. Bouillaud, J.-F. Rossignol
The paper investigates how thiazolides, specifically Nitazoxanide, reduce viral release by mildly uncoupling mitochondrial oxidative phosphorylation, showing this effect is significant even with modest deviations from normal.
bioRxiv · Sep 16, 2022 · PreprintBiochemistry